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Selenium-Dependent Regulation of Seleno-GPxs The incorporation of Sec in the peptide sequence of seleno-GPxs is an important requirement for the synthesis of functionally active seleno-GPxs (Fig

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The standard dose escalation begins at 2.5 mg subcutaneously once weekly for four weeks, followed by increases to 5 mg, 7.5 mg, 10 mg, 12.5 mg, and finally 15 mg at four-week intervals as tolerated

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